Unexplained weight loss, defined as significant unintentional reduction in body weight, may indicate underlying health issues such as hyperthyroidism, diabetes, or cancer. Hyperthyroidism accelerates metabolism, causing weight loss despite increased appetite, often with symptoms like anxiety and rapid heartbeat.

Diabetes, particularly type 1, leads the body to burn fat and muscle for energy, resulting in weight loss alongside thirst, frequent urination, and fatigue. watch more.